HCG injection when ovulation occurs. The effect of hCG injection on the follicle

And hormonal disruptions in the female body. The techniques are used for in vitro fertilization, artificial insemination, hormonal or age-related changes.

The technique consists of taking hormonal drugs for development, prescribed individually, and then injecting a drug with human chorionic gonadotropin to trigger ovulation.

Stimulation of follicle development and egg release is used in cases where a couple is unable to conceive a child on their own. The gynecologist makes a decision on treatment after conducting the necessary examinations.

The length of the period (from 6 months to 1 year) during which the woman is trying to get pregnant is also taken into account.

Human chorionic gonadotropin, which is secreted by the chorion during natural processes in the initial stages of pregnancy, is used for.

Follicle rupture under the influence of this hormone occurs due to its follicle-stimulating and luteinizing properties. HCG regulates the maturation of the dominant follicle, its rupture (i.e. ovulation), the formation and development of the corpus luteum. The administration of the hormone also prevents the development of follicular cysts on the ovary.

Gonadotropin will perform its functions if the injection is given 1 - 1.5 days before expected ovulation. The fact of ovulation or its absence is confirmed by ultrasound.

Hormone injection is not a treatment method. Follicle rupture is provoked at a time, only in the cycle when the drug was administered. The injection will not affect subsequent menstrual cycles. In addition, the absence of ovulation should be recorded by a specialist during several cycles in a row.

When is it prescribed?

During an ultrasound, the gynecologist determines the “” follicle and monitors its development. for the period when it has matured and the release of the egg is approaching.

The injection is given once before ovulation. The dosage is selected individually and ranges from 5000 to 10,000 units. Gonadotropin is injected into the gluteal muscle or thigh.

Sometimes repeated administration of the hormone is required to support and develop the corpus luteum, which maintains pregnancy.

ATTENTION! It is unacceptable to make an independent decision about a drug injection. Using the drug without a doctor’s recommendation will lead to serious hormonal disruption in a woman’s reproductive system.

After the injection, the doctor selects the optimal frequency of sexual intercourse for pregnancy or prescribes artificial insemination. Usually required every other day or daily, depending on the spermogram.

At what size is it done to stimulate a rupture?

Intramuscular administration is prescribed after identifying the dominant follicle. With hormonal stimulation, follicles. The doctor uses an ultrasound examination to determine their readiness for ovulation.

The gynecologist prescribes an injection for successful exit when the follicle size reaches 16–21 mm. In each individual case, the doctor individually determines readiness for ovulation.

Within 36 hours after the injection, ovulation occurs and the possibility of artificial or natural insemination occurs.

IMPORTANT! If you administer the drug before the prescribed time, then if ovulation occurs, a non-viable egg will be obtained and pregnancy will not occur.

In what cases should the injection not be used?

Contraindications to stimulation:

hypersensitivity to the drug human chorionic gonadotropin or its component;
the presence of a malignant neoplasm, the growth of which can be facilitated by the hormone (as well as suspicion of oncology of the ovaries, uterus, mammary glands, pituitary gland);
menopause period;
lactation;
obstruction of pipes;
thrombophlebitis;
hypothyroidism;
pathologies of the adrenal glands.

IMPORTANT! If gonadotropin stimulation is performed on a woman with tubal obstruction, the process may result in an ectopic pregnancy. It is necessary to eliminate the obstruction by laparoscopy.

A contraindication to the procedure may be the patient’s age over 37 years, but in this case the gynecologist makes the decision individually.

What if it doesn't burst?

Ovulation after administration of human chorionic gonadotropin occurs in the vast majority of cases. But there are situations in which the break still did not occur. The reasons may be different:

improper stimulation of follicle development;
absence of a dominant follicle;
the presence of other health problems that were not previously taken into account.

An injection with a hormonal drug is given only if the patient’s ovaries are under constant monitoring and folliculometry is regularly performed using ultrasound. Otherwise, hCG will not promote ovulation, since there will be no dominant follicle.

If the follicle does not rupture 36 hours after the injection, the doctor decides to carry out one of the following measures:

administration of an additional hCG drug (for example, 5000 U of the hormone to the already administered 10,000 U);
repetition of stimulation during the next menstrual cycle;
break and repeat stimulation after three menstrual cycles.

IMPORTANT! A cyst may form in place of the unruptured follicle. Monitoring the process is important both when ovulation occurs and when it does not occur.

Possible complications and adverse reactions

The alleged complications are explained by the effect of the drug on the body of a particular person. Allergic reactions in the form of a rash at the injection sites are possible.

Adverse reactions occur, which are described in the annotation for the drug used:

nausea and vomiting;
diarrhea;
soreness of the mammary glands;
pain in the ovarian area;
thromboembolism;
hydrothorax;
temperature increase;
gynecomastia.

Taking into account all possible complications, gynecologists decide whether to use the hormone to achieve a long-awaited pregnancy, or refuse it.

Women planning to have a baby are faced with many unfamiliar medical terms. Their meaning remains a mystery until you experience them in person. These include the hCG hormone, which is produced by the female body after fertilization and is responsible for the proper development of the fetus. But sometimes a failure occurs and its artificial introduction is required. This is possible with the help of special injections that contain a substance - human chorionic gonadotropin. It is given during pregnancy planning to women who do not ovulate.

Under what circumstances is an HCG injection needed?

The ability to become pregnant occurs only when the egg is released from the ovary. This occurs somewhere in the middle of the menstrual cycle. Sometimes the fertilized egg does not attach to the wall of the uterus. The couple tries for a long time, but nothing works, since the long-awaited ovulation does not occur. It can be caused by stimulation, but to do this it is necessary to find out the causes of the failure and eliminate them.

An injection of hCG can restore ovulation, but the choice of drug and its dosage is prescribed only by a doctor based on the characteristics of each woman individually. After the administration of the chosen remedy, the favorable period should occur in a day or a day and a half, but this is an approximate time, because sometimes ovulation occurs much later.

to stimulate the egg and prevent the formation of a cyst, which can occur when the follicle does not burst, but begins to decrease in size;
in cases where the placenta is not developing well. An HCG injection is administered to help her. He contributes to its formation;
to preserve the functionality of the corpus luteum. In the initial stage of pregnancy, the body really needs its support, then the placenta can take over this function;
at risk of miscarriage. Especially if they have already been present in previous cases of pregnancy;
in case of artificial insemination.

Important! During stimulation, the success of follicle development must be monitored by ultrasound. In case of male infertility, injections with hCG are useless.

If after all the examinations it turns out that such a procedure cannot be done without, then it is necessary to provide the doctor not only with the results of the woman’s tests, but also with her partner. He is required to take a spermogram to accurately verify a man’s ability to conceive. This can be understood by the quality of his seminal fluid. Many representatives of the stronger half believe that if they have not had problems before and their older children are proof of this, then they are deeply mistaken. The situation may change within a year and it does not matter how many children there were before.

In what cases should you not do hCG?

Before stimulation, you need to take tests to check your hormones. This is necessary to clarify their exact indicators; it is better to do this several times. After discovering the problem, the doctor will probably prescribe a course of normalizing hormone levels, and if this therapy does not help, then you will need to resort to an injection of hCG.

But there are hormones in violation of which stimulation cannot be carried out, these are:

prolactin;
thyroid gland;
and almost all of them are male.

They can interfere with the process, and it will be inconclusive.

It is strictly forbidden to give injections with hCG if the following diseases are observed:

tumors of the ovaries and pituitary gland;
hypothyroidism – lack of thyroid hormones;
existing blood clots in the vessels or a predisposition to their appearance;
early menopause;
sensitivity to the ingredients of the injection.

Important! If tubal obstruction is detected, then stimulation of ovulation can lead to ectopic conception. Therefore, before the procedure it is necessary to undergo laparoscopy and metrosalpingography.

Indications for ultrasound monitoring for hCG

On average, a woman's monthly cycle lasts 28 days, so the first ultrasound can be done 10 days after the last menstruation. The procedure should be carried out every three days until the ovulation period is established or the next “women’s days” begin.

The results of observations can be:

lack of ovulation because the ovaries do not work and the follicles do not mature;
the main follicle matures, but does not grow to the required size and ovulation does not occur;
the follicular sac develops normally, but then does not rupture.

Stimulation is not required only if ovulation occurs and the corpus luteum forms in the follicle. And if it does not open in time, you can help it do so with a timely injection of hCG, after which a corpus luteum will appear in place of the follicle.

Stimulation procedure

The doctor usually prescribes an injection with human chorionic gonadotropin on the second day of the cycle. It must be done daily, and after ten days the stimulation stops. The whole process takes place under the supervision of a doctor, who also prescribes how many days the injections should be given and what should be the dose of the administered medication.

Important! There is no need to rely on averages or performing stimulation on friends. For each patient, everything goes individually, this is due to the structural features of the ovaries and uterus of an individual woman.

Treatment is accompanied by constant monitoring by ultrasound every three days. The first is carried out after stimulation on the fifth day. And when the follicles grow to the required size (approximately 20-25 mm), then a final examination is carried out, checking their opening. To complete it successfully, an injection of hCG is administered; during this period, it provokes the start of ovulation.

If all circumstances are favorable, the injection will take effect within 36 hours and ovulation will begin. After this is confirmed by ultrasound, hormonal injections with utrogestan and progesterone, which are needed to support the activity of the ovaries, will be prescribed.

How much and when sexual intercourse should be performed during stimulation is prescribed by the doctor; this is influenced by the male factor. After completing the injection, you can try again the next day. They must be repeated until the corpus luteum appears, that is, until the period when ovulation occurs.

An increase in hCG begins to be observed already on the third day, and every 3 days it doubles. Under the influence of the administered injection, the body begins to produce progesterone and estrogen at double speed, and they promote conception.

The hCG injection is often used in gynecology to stimulate ovulation; it effectively helps with infertility and promotes the speedy conception of a long-awaited baby. After its administration, you do not have to wait long for results, and in most cases they are positive.

In the proposed video, a specialist will clearly explain the significance and effect of the hCG injection.

Injections at home - review of prices and quality from professionals

Many patients are concerned about the answer to the question: “The hCG 5000 injection was performed, how long after ovulation?” To understand the principle of action of human chorionic gonadotropin, you need to carefully understand its properties.

This hormone is indispensable if a woman plans to conceive and carry a child. However, there are situations when not enough of it is produced naturally, and it is because of this that pregnancy is impossible. In such a situation, a doctor may prescribe an injection of a synthetic analogue of this hormone.

Ask your gynecologist when ovulation occurs after an hCG injection. Here, a lot depends on the amount of active substance and the individual characteristics of the expectant mother’s body.

HCG injections for ovulation are made from a protein structure contained in the urine of a woman carrying a baby. The substance can activate the natural production of sex hormones. HCG for injection can have different medical names - Menogon, Novarel, etc. The doctor performs an injection with a special insulin syringe into the groin area. The main indications for such a procedure can be considered:

Pathologies accompanied by ovarian dysfunction.
Painful periods, clear signs of PMS.
Infertility is associated with the lack of release of an egg or the formation of a dominant follicle.
Suppression of the corpus luteum.
Frequent cases of spontaneous abortion.
Stimulation of the formation of an active egg during preparation for the IVF protocol.

Ovulation

With some ovarian pathologies, ovulation is impossible and the patient is unable to become pregnant. This situation is possible due to polycystic disease, neoplasms, and even prolonged stress.

The follicle with the egg may not form at all or may not form completely. In some patients, a mature egg is not able to exit the corpus luteum. It is recommended that the patient be given an injection of hCG to activate the production of follicles and the formation of a healthy egg.

Immediately before the procedure, you must undergo a diagnostic test. If during an ultrasound examination the physician discovers that follicles are beginning to form, a hormone injection is prescribed, with a dosage of 1500 - 5000 units. If the patient is preparing for artificial conception and superovulation is needed, a substance with a volume of 10,000 units is administered.

How long does it take to ovulate after an HCG 10,000 injection? Doctors say that the egg is fully formed and leaves the ovary within 1-1.5 days after the procedure. To monitor the patient's condition, an ovulation test and ultrasound are performed. If the egg is not mature, it is recommended to increase the dosage in the next menstrual cycle.

A maximum of 36 hours after the injection of hCG 10,000, full ovulation should occur. If you are planning a pregnancy, try to have as many sexual acts as possible in a given period of time.

There are cases when, after the administration of the hormone, ovulation does not begin, but the corpus luteum continues to develop and gradually transforms into a cyst. An hCG injection is a single stimulation procedure, but not a method of treating infertility.

There is no need to take an ovulation test within 3 days after the injection, as it is guaranteed to be positive. If conception has occurred, the hCG hormone in the body begins to rise. A decrease in the concentration of the substance in the blood may indicate a threat of miscarriage, ectopic pregnancy, placental insufficiency, or pathologies of embryo development.

To determine the exact cause of the decrease in the production of the hCG hormone, the patient needs to undergo an ultrasound examination. With normal fetal development, the concentration of the hCG hormone increases until the 11th week, and then decreases and stops at a certain level until the baby is born.

Complications

Any introduction of a hormonal drug disrupts the natural processes in the body. As a result of an incorrectly selected concentration, the patient may experience complications - a cyst, fluid accumulation, thrombosis, hyperstimulation, accompanied by shortness of breath, abdominal pain, and strong heartbeat.

Some patients may experience nausea, vomiting, or depression after administration of hCG. As soon as the treatment is over, the unpleasant symptoms will disappear.

An injection of the hCG hormone is necessary to stimulate ovulation and further support pregnancy. This treatment is prescribed to patients who do not have enough natural hormones or have certain pathologies in the functioning of the ovaries.

The physician individually selects the appropriate course of therapy and dosage of the drug for each patient. Pregnancy should occur in the first few cycles after the injection.

Chorionic gonadotropin (CG) is a hormone that is produced by chorionic tissue immediately after implantation. Normally, it is present in the body only during pregnancy. Thanks to medical advances, this hormone is created artificially for the purpose of treating anovulation (a cycle disorder that makes natural conception difficult). Why and when are hCG injections indicated? What is the result of such therapy?

Mechanism of action of hCG injection

Chorionic gonadotropin is involved in the synthesis of sex hormones, has a positive effect on the process of egg maturation and the key event of the cycle - ovulation. It is used to stimulate the release of the oocyte, if for some reason this process does not occur independently and anovulatory cycles are observed (rapid tests for ovulation are negative).

An injection of hCG promotes ovulation and supports the functioning of the corpus luteum (a temporary endocrine gland that produces the hormone progesterone until the 16th week). Previously, in the first phase of the cycle, follicle growth is stimulated under the influence of an estrogen substitute. When ultrasound shows its maturation to 2.5 cm in diameter, an injection of human chorionic gonadotropin is given. It is taken into account that two days have passed since the last dose of the stimulant Clostilbegit.

Ovulation occurs 1-1.5 days after the administration of the hormonal substance. Within two days, a period favorable for fertilization begins, which future parents should take advantage of. A woman’s own feelings, as well as a special pharmacy test, will tell her about the moment of ovulation. It will show a reliable result before the hCG injection, after which the rupture of the follicle can be seen by ultrasound.

How long the drug is eliminated from the body depends on individual characteristics. Typically, no traces of the substance are detected within 3-5 days. To do this, you should drink more fluid.

Types of hCG

HCG injection may be needed for:

stimulation of follicle rupture after treatment with Clostilbegit;
maintaining the life of the corpus luteum;
support pregnancy until the 16th week, until the placenta is formed.

To produce hCG preparations, proteins extracted from the urine of expectant mothers are used. In Russia you can purchase domestic and imported products. They are prescribed by doctors strictly according to indications. Self-medication can lead to hormonal disorders in the female body.

The dosage of hCG drugs is selected individually and is 500, 1000, 1500, 5000, 10000 units. The following drugs are distinguished by name: Pregnil, Horagon, Ecostimulin, human chorionic gonadotropin. The cost of drugs depends on the manufacturer, pharmacy markups, and dosage. On average, an HCG injection will cost 1,500 rubles.

In what cases is it prescribed?

Indications for injections of hCG medications:

anovulatory cycles;
supporting the functioning of the corpus luteum;
preparation for IVF at the stage of ovulation stimulation;
threat of pregnancy failure in the early stages;
history of recurrent miscarriage;
menstrual irregularities.

Stimulation with hCG drugs is indicated for underdevelopment of the genital organs, dysfunction of the hypothalamus and pituitary gland. In gynecology, they can additionally be prescribed for dysmenorrhea and menstrual pain associated with this pathology, nausea, and loss of consciousness.

Contraindications to hCG injection

When prescribing the drug, the doctor takes into account the patient’s age, health status and existing contraindications:

individual intolerance to the components of the product;
a number of diseases of the endocrine system, including the thyroid gland;
early menopause;
oncopathology of the female reproductive system;
tendency to thrombosis;
lactation period;
adhesions in the pelvis.

If there are contraindications or as prescribed by a doctor, ovulation stimulation is performed without the administration of hCG, only through the administration of Clostilbegit. In this case, the follicle bursts on its own after maturation, which is shown by an ovulation test. However, this does not always happen.

Instructions for use of injection

HCG preparations are produced in the form of a ready-made solution or components for its preparation (powder and water). The injection should be entrusted to a physician, since the place of intramuscular injection is the abdominal area. The dosage and time of administration are selected by the obstetrician-gynecologist. Most often, drugs are used in dosages of 1000, 5000, 10000 units.

Preparation for the procedure

After the injection of the hormone, the likelihood of pregnancy is very high, so it is worth preparing for the procedure in advance. To do this, it is important to get rid of bad habits and stress, and establish a healthy lifestyle. Normalization of weight plays an important role - its excess and deficiency can become an obstacle to successful conception and pregnancy. In parallel, it is recommended:

testing the hCG drug for individual intolerance;
testing for immunological compatibility with a partner, STIs;
examination by a therapist;
Ultrasound of the uterus and appendages;
diagnostics of pipe patency;
a course of hormonal therapy and hysteroscopy (if necessary);
checking the quality of the future father's sperm (spermogram).

After collecting anamnesis, the doctor determines the type of drug, prescribes its dosage and time of administration. On the specified day, the patient comes to the medical office for an injection.

How is the required dose selected?

The dosage is determined depending on the goal set by the doctor. An injection of hCG to stimulate ovulation is given with a dosage of 5000 units after detection of a dominant follicle. Superovulation before IVF is induced using the drug at a dosage of 10,000. The ovulation process is monitored by ultrasound. For maintenance therapy, dosages of 500 and 2000 IU are used. Injections are indicated on days 3, 6, 9 after ovulation.

If there is a threat of miscarriage in the early stages, make sure that there is no ectopic pregnancy (see also: hCG level in the early stages of ectopic pregnancy). Initially, the drug is administered at a dosage of 10,000 IU, and then 5,000 weekly. Therapy can last up to 14 weeks. In parallel, to maintain the desired level of progesterone, Duphaston or Utrozhestan are indicated (we recommend reading: how to take Duphaston: before or after meals?).

How and when is the injection given?

The drug is administered intramuscularly with an insulin syringe with a thin needle. The doctor determines where to inject. To stimulate ovulation, it is placed in the stomach, for which a distance of 2 fingers is removed from the navel to the side. The area is treated with alcohol. Then the skin fold is pinched and the syringe needle is inserted. An alternative for injections is the buttock area.

When stimulating ovulation, gonadotropin will perform its functions if the injection is given 1-1.5 days before expected ovulation. This process is monitored by ultrasound, the injection is given 10-14 days after the start of the menstrual cycle. The rupture of the follicle occurs precisely during the period when the injection is given. The injection does not affect subsequent cycles.

To maintain the function of the corpus luteum, pregnant women may be prescribed maintenance therapy with hCG. Typically, injections are given 3, 6, 9 days after the follicle ruptures.

When diagnosing pregnancy, the hCG level is constantly monitored. If its level decreases or there is a threat of miscarriage, maintenance therapy is indicated. The dosage is selected depending on the symptoms, tests, and the woman’s health condition.

What side effects might there be?

Side effects after an injection of hCG, which are observed in case of disruption of the administration process and overdose:

untimely ovulation, which, if the endometrium is unprepared, leads to termination of pregnancy;
accumulation of fluid in the abdominal cavity;
allergy manifestations from the skin, respiratory organs;
depression;
irritability;
fast fatiguability.

The most serious complication is ovarian hyperstimulation syndrome, in which many follicles grow at the same time. They do not burst, but develop into cysts, which is dangerous to health and leads to cardiac and respiratory failure and other serious consequences. Concomitant use of the drug with glucocorticosteroids in large dosages is not recommended.

If pregnancy does not occur as a result of therapy, you need to prepare for further treatment. Perhaps the long-awaited conception will happen naturally 2-3 months after hormonal intervention. Modern reproductive specialists have enough technology at their disposal to help a woman become a mother.

One of the most popular methods of treating infertility is ovulation stimulation. It is used for women with problems with the maturation of the egg and the absence of its release from the ovary. To stimulate ovulation, hormonal drugs are used, thanks to the action of which one or more eggs capable of fertilization are formed in the female body.

In our Remedial Practice we will test you step by step. Once a gestational carrier has been selected, she must undergo a thorough examination. Once all assessments are completed, the treatment cycle can begin. Both the gestational carrier and the donor mother begin taking pills and injections to synchronize their cycles and prepare for embryo transfer. The donor mother takes the eggs to stimulate her ovaries to produce eggs, and at the same time the carrier takes medications to prepare the uterus for implantation.

After embryo transfer, the gestational carrier asked to reduce excessive physical activity for several days. After the transfer you will be given and a pregnancy test will be done approximately 10 days later. If it is positive, it indicates that implantation has been achieved.

Methods to restore ovulation are selected taking into account the reason for its absence. Achieving a positive effect from the use of ovulation stimulation is possible only if the cause that disrupts the ovulatory process is established.

Reasons for the development of anovulation

The reasons that provoke the development of anovulation can be physiological and pathological (chronic). Physiological anovulation is considered normal and does not require seeking medical help and may occur during the following periods in a woman’s life:

The first ultrasound to evaluate pregnancy is scheduled approximately 3-4 weeks after the transfer. If the pregnancy test is negative, all treatment is stopped and menstruation usually begins within three to ten days. If frozen embryos exist, the process can be started again.

Preimplantation genetic diagnosis

These cells and embryos freeze. The biopsy cells are analyzed and we get a report that tells us if the embryos have a normal number of chromosomes or not. We also learn about fetal sex. This process significantly increases the chances of pregnancy, reducing the incidence of multiple pregnancies and abortions. This also reduces the number of embryos that are saved, since only normal ones remain frozen. These embryos, without genetic defects, are transferred into a future cycle.

Puberty: In teenage girls, ovulation may not occur for the first two years after menarche;
period of pregnancy and breastfeeding;
menopause;
“rest” period: 1-2 menstrual cycles per year; women of reproductive age may not ovulate.

Pathological anovulation can be caused by a violation of the structure of organs or diseases of the endocrine system. Most often, the presence of this particular condition is the cause of infertility.

Not all methods offer this procedure. Laparoscopy is a minimally invasive surgical procedure that allows for a complete examination and evaluation of the female pelvic region and abdominal structure. This is an outpatient surgery performed under general anesthesia. The incisions are half a centimeter, so the patient can go home the same day and work within a few days. Pelvic adhesions, endometriosis, tubal, ovarian and uterine abnormalities, evidence of past infections, are some of the things we can diagnose with these procedures.

Pathological reasons for the lack of ovulation may be the presence of the following conditions:

Hypothalamic dysfunction;
oncological diseases of the pituitary gland;
circulatory disorders in the brain;
hyperprolactinemia;
hyperandrogenism;
frequent stress;
injuries of the reproductive system;
inflammatory diseases of the appendages;
obesity;
anorexia;
premature menopause;
(polycystic ovary syndrome, endometriosis, uterine fibroids, etc.);
diseases of the thyroid gland and liver;
when taking hormonal contraceptives.

A large percentage of patients who have all normal fertility tests have problems in the pelvic area. Many times these anomalies can be repaired simultaneously. Thus, this operation serves as a diagnosis, helps us plan next steps, and often improves the chances of pregnancy. Photos are taken before, during and after surgery. Most patients are discharged and can return home after the procedure.

Hysteroscopy is an outpatient surgical procedure performed under anesthesia. A 4-6 mm camera is inserted behind the cervix to enter the uterine cavity. Using fine instruments such as tweezers and scissors, abnormalities such as polyps, fibroids, scars and septums are corrected. Typically, these abnormalities can be corrected in one session without making any incisions. Typically, patients can return to work the next day. Most patients are discharged within a couple of hours.

Diagnosis of anovulation

To diagnose anovulation, it is not enough to draw a basal temperature chart, since this method is not reliable enough. More informative ways to identify this pathology are: ultrasound examination, carried out over several menstrual cycles, as well as tests to determine the level of certain sex hormones.

Reversal of tubal ligation

To be able to perform this procedure, it is important that your tubes are blocked but not destroyed. We need at least 4-5 centimeters of a regular horn to use. It is also important that your partner has a normal sperm test so you can become pregnant after surgery. The operation itself takes about two hours. The incision measures 5-2 inches and is located in the pubic area covered by the “bikini”. The patient is discharged the same day and takes about two weeks to recover and return to daily life.

Tests for hormone levels in the blood

Stimulation of ovulation is not prescribed if there are deviations from the norm in the blood levels of thyroid hormones, prolactin and male sex hormones.

Ultrasound monitoring

In order to confirm or exclude the absence of ovulation, it is necessary to conduct multiple ultrasound examinations throughout the entire menstrual cycle.

Stages of ovulation stimulation

The chances of pregnancy depend on the type of tubal ligation, the woman's age, other female factors, and the man's test sperm. However, since the middle of the last century, some weight management clinics have also administered the substance as an aid to weight loss. In recent years, this substance has increased in popularity for this purpose and is usually administered as an injection or sublingual drops.

History as a weight loss assistant

This hormone is an aid in the production of its hormonal compound progesterone, which dilates the uterus and helps nourish the fetus. While studying pregnant women in India, he realized that those in a calorie deficit lost fat instead of muscle. After a complete medical examination and pre-detoxification for detoxification, the patient receives daily injections or self-administers for the same number of days as the protocol lasts. The patient also follows a strict, extremely low calorie diet until the end of the program and then a high calorie maintenance diet.

If the cycle is 28 days, the first ultrasound is scheduled for 8-10 days after the last menstruation has ended. Then the study is repeated at intervals of 2-3 days until the onset of ovulation or the beginning of the next menstruation.

Stages of ovulation stimulation

Stimulation using clostilbelite begins on the fifth day of the menstrual cycle, with gonadotropins - on the second. The timing of the start and duration of taking the drugs is determined by the attending physician in accordance with the condition of the woman’s uterus and ovaries.

After this, the patient must stop the protocol, but must still follow a low-calorie diet for at least three weeks. However, the injections themselves last approximately three days each. This hormone begins to be produced immediately when the fertilized egg begins to run.

Although it is possible to take a pregnancy test before this time, the chances of getting a false positive result are extremely high if you decide to take your chances. With that in mind, there's no reason why he shouldn't take a pregnancy test around 12 days in advance.

The first ultrasound examination is carried out a few days after the start of the ovulation stimulation procedure. Then ultrasound is repeated every 2-3 days until the follicles reach a size of at least 20 mm. After this, the woman is given an injection of hCG (in a dosage of 5,000 to 10,000 units), which starts the ovulation process and prevents regression of the follicles and the risk of follicular cyst formation.

An hCG injection is an injection of a hormonal drug with the main active substance - human chorionic gonadotropin: pregnyl, prophasia, choragon, humegon, menogon, choriogonin, etc. With the help of these drugs, the ovulation process is restored, as well as an increase in the level of hCG in the blood, due to which yellow body and its activity increases.

The doctor selects the dosage of the hCG drug in each individual case in accordance with hormone levels, the size of the follicles and a number of other equally important factors. Excessive amounts of human chorionic gonadotropin can trigger the development of ovarian hyperstimulation syndrome.

An injection of hCG (human chorionic gonadotropin) triggers the onset of ovulation, which usually begins 24-36 hours after the injection. The release of the egg is recorded using ultrasound, after which the woman is prescribed additional support for the ovaries (corpus luteum) in the form of injections of utrogestan or progesterone.

The timing and frequency of sexual intercourse or artificial insemination when stimulating ovulation is prescribed by the doctor individually, depending on the results of the man’s spermogram. If the quality and quantity of sperm are good, it is recommended to have sexual intercourse every day or every other day, starting from the moment the woman received the hCG injection until the corpus luteum is formed.

What is an HCG injection?

The main factor influencing a woman’s ability to become a mother is the presence of ovulation - the process of release of mature eggs from the follicles and subsequent movement through the fallopian tubes, which determines readiness for fertilization. Sometimes, for one reason or another, a malfunction occurs in the body, as a result of which the membrane (follicle) does not rupture.

The success of conception largely depends on the level of the hormone human chorionic gonadotropin in a woman’s blood, the effect of which on the corpus luteum continues until the fertilized egg attaches to the wall of the uterus. In some cases, there is a need for artificial administration of human gonadotropin (hCG injection).

In what cases is a hCG injection indicated?

An hCG injection can be prescribed to women in the following cases:

In the absence of ovulation: an injection of hCG stimulates the release of the egg and prevents the reverse development of follicles (atresia). Unruptured follicles may regress, decreasing in size and forming follicular cysts;
to preserve the vital activity of the corpus luteum: an injection of hCG helps maintain the condition of the corpus luteum until these responsibilities are “transferred” to the placenta;
for the normal formation of the placenta and maintenance of its functions: when the development of the placenta is inhibited;
if the female body is unable to maintain pregnancy and has a history of miscarriages;
if there is a risk of miscarriage;
when planning in vitro fertilization.

HCG injection: contraindications for injection

HCG injection is not prescribed for women suffering from the following pathologies:

Malignant ovarian tumors;
pituitary tumor;
predisposition to the formation of blood clots in blood vessels;
violation of the patency of the fallopian tubes;
hypothyroidism (insufficient amount of thyroid hormones);
individual intolerance to one or another component of the drug to stimulate ovulation;
with early menopause;
during breastfeeding.

Pregnancy after hCG injection

An hCG injection can cause a false positive result if a pregnancy test is performed earlier than 14 days after ovulation. This is explained by the fact that these tests are based on determining the level of hCG, which is an indicator of the onset of conception, and the artificial introduction of this hormone increases its amount in the blood for a while. A more reliable method is dynamic monitoring of hCG, the level of which in pregnant women is constantly increasing until the end of the first semester. At the beginning of the second semester, it gradually decreases to a certain level, which remains unchanged until the end of pregnancy.

HCG is a hormone that is released into a woman’s blood immediately after the fertilized egg is implanted in the uterus.

The level of this substance in the blood is constantly growing, with its help you can find out whether everything is fine with the fetus. But this hormone is prescribed when planning conception, so many women are interested in the question of whom the hCG injection helped to get pregnant.

How does the hCG injection work?

Usually this injection is prescribed only once when planning pregnancy. This hormone promotes the rupture of the dominant follicle and stimulates ovulation. This medicine is prescribed only after the woman takes hormones for the growth of the dominant follicle.

Every 2 days the follicle is monitored, and when it reaches the desired size, hCG is administered. After administration of the drug, ovulation occurs within 12-36 hours. It is during this period that you need to have sex during natural conception or introduce sperm through insemination. Reviews indicate that the injection helps to get pregnant.

When is an HCG injection prescribed?

There are two options for administering the hormone:

stimulation of ovulation with Clostilbegit;
with polycystic ovary syndrome, when the follicle grows, but does not burst, but develops into a cyst.

Therefore, an hCG injection is prescribed for anovulatory cycles, when the egg does not mature. Stimulation is carried out with Clostilbegit or Clomid. On days 14-20 of the cycle, the hCG hormone is administered. During insemination, sperm is injected only after follicle rupture is confirmed.

The hCG hormone helps to get pregnant and maintain pregnancy. When artificially inducing ovulation after administration of human chorionic gonadotropin, progesterone is prescribed. Usually this is the drug "Utrozhestan" or "Duphaston". They loosen the endometrium and promote the attachment of the fertilized egg.

Indications for the use of hCG:

anovulation;
corpus luteum deficiency during pregnancy;
habitual abortion;
risk of miscarriage.

When can I take a pregnancy test after an injection?

It is worth considering that pregnancy test strips react specifically to this hormone. Therefore, before the expected date of your period, you will receive false positive results. Only after a few days of delay does it make sense to do a test.

If you don’t have enough patience and want to find out about your pregnancy as soon as possible, then donate blood for hCG. Based on the amount of hormone in the laboratory, they can judge the absence or occurrence of pregnancy.

When does it make no sense to inject hCG?

This injection is not prescribed at random. It must be done on a certain day of the cycle when the follicle is fully mature. If you administer the medicine earlier, ovulation will occur, but you will receive an underdeveloped egg that is not capable of developing into pregnancy.

Therefore, the substance is administered only with constant folliculometry using ultrasound. If you have not been injected with drugs to stimulate the growth of the dominant follicle, then the injection is also useless, since there will be nothing to rupture due to the absence of the “main” follicle.

How to determine that pregnancy is developing by hCG levels?

This hormone is included in mandatory screening of pregnant women. The concentration of this substance is used to judge the health of the fetus. At 14-18 weeks, the pregnant woman donates blood for hCG. If it is reduced, it means that there is a threat of miscarriage or the presence of pathologies in the fetus.

What to do if hCG is low during pregnancy?

If during testing it turns out that the concentration of this substance is low, the hormone is administered by injection to preserve the embryo. The fact is that this substance controls the release of progestins and estrogens into the blood. If there are more or less of these hormones, there is a risk of miscarriage. In addition, human chorionic gonadotropin is prescribed for insufficiency of the corpus luteum, which supplies the fertilized egg with useful substances.

An increased concentration of hCG indicates:

about multiple pregnancy;
about maternal diabetes;
about taking progestins;
about Down syndrome in the fetus;
about an incorrectly determined gestational age.

Therefore, if you are taking Duphaston or Utrozhestan when there is a threat of miscarriage, tell the laboratory about it. Usually, it is not the concentration of hCG itself that is analyzed, but its relationship to AFP and estriol. Based on the data obtained, a diagram of the risk of genetic defects in the fetus is constructed, since an increased level of the hormone is an indication for the analysis of amniotic fluid, which is collected by puncturing the mother’s abdomen. This increases the risk of infection and miscarriage.